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Results
MRI showed 63-67% accuracy, 57-59% sensitivity, 70-80% specificity, 75-81% PPV and 52-56% NPV in identifying ypT0-2. MRI accuracy in N staging was %57-63, sensitivity %54-60, specificity %58-65, PPV 40-48% and NPV 71-76%. MRI accuracy in predicting complete response to neoadjuvant chemoradiotherapy was %78-84, sensitivity %14-20, specificity %87-92, PPV 11-23% and NPV 89-90%. Interobserver agreement was 0.977, 0.864 and 0.756 for T staging, N staging and predicting complete response,...
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Conclusion
In this study, the specificity and PPV of MRI in T staging was higher. In N staging, NPV was determined to be higher with MRI. The specificity and NPV of DWI was higher in predicting complete response to neoadjuvant chemoradiotherapy.
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Purpose
This study aims to determine the efficiency of high resolution rectal MRI in preoperative local staging of the rectal cancer after neoadjuvant chemoradiotherapy.
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Material and methods
136 patients with locally advanced rectal cancer, who were treated with preoperative chemoradiotherapy followed by total mesorectal excision were analyzed. Patients underwent MRI before and after neoadjuvant chemoradiotherapy. MR examinations were performed on a 1.5 T MR system with pelvic phase arrayed coil. High-resolution T2W turbo spin echo scans in coronal, sagittal and axial planes and diffusion-weighted (b=0,b=1000 mm2/s) images(DWI) in sagittal and axial planes were acquired. The...